Lower Limit of Detection |
0.03 pg/mL |
Lower Limit of Quantification2 |
0.08 pg/mL |
Upper Limit of Quantification |
20 pg/mL |
Low-end CV% Range |
5 - 9% |
Low-end CV% Average |
7% |
Recommended Sample Volume |
10 µL |
Minimum Sample Volume Required3 |
1 µL |
Representative data shown for demonstration purposes only. Individual results may vary depending upon samples tested and protocol used.
Granulocyte-Colony Stimulating Factor (G-CSF) is an endogenous hematopoietic agent activated and expressed by many types of cells, including macrophages, tumor cells, fibroblasts and endothelial cells. One of the main functions of G-CSF is to regulate formation of neutrophils during hematopoiesis, which are important for proper immune function. For example, in cancer patients, reduced hematopoeisis from chemotherapy results in low neutrophil production, which jeopardizes the immune system, leaving the body susceptible to infectious attacks. G-CSF therapy has been shown to restore hematopoiesis in cancer and leukemic patients by stimulating white blood cell production. Interestingly, G-CSF has also demonstrated effectiveness in improving cardiac function following a myocardial infarction.
Protein Name: |
Granulocyte colony-stimulating factor |
UniProtKB/Swiss-Prot ID: |
P09919 |
Protein-protein interaction database: |
P09919 |
Alternative Names: |
Pluipoietin, INN=Filgrastim, INN=Lenograstim |
Gene Names: |
CSF3 |
Synonym Gene Names: |
c17orf333, GCSF |
Function: |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
Biological Processes: |
cytokine-mediated signaling pathway, granulocyte differentiation, immune response, positive regulation of cell proliferation |
Molecular Function: |
cytokine activity, enzyme binding, granulocyte colony-stimulating factor receptor binding, growth factor activity |
|
GM-CSF |
Erenna® GM-CSF Immunoassay Kit |
03-0067-xx |
IFN-γ |
Erenna® IFN-γ Immunoassay Kit |
03-0049-xx |
IL-1α |
Erenna® IL-1α Immunoassay Kit |
03-0050-xx |
IL-1β |
Erenna® IL-1β Immunoassay Kit |
03-0030-xx |
IL-10 |
Erenna® IL-10 Immunoassay Kit |
03-0056-xx |
IL-12 |
Erenna® IL-12 Immunoassay Kit |
03-0057-xx |
IL-13 |
Erenna® IL-13 Immunoassay Kit |
03-0069-xx |
IL-15 |
Erenna® IL-15 Immunoassay Kit |
03-0058-xx |
IL-17A |
Erenna® IL-17A Immunoassay Kit |
03-0017-xx |
IL-17A/F Heterodimer |
Erenna® IL-17A/F Heterodimer Immunoassay Kit |
03-0073-xx |
IL-17F |
Erenna® IL-17F Immunoassay Kit |
03-0018-xx |
IL-2 |
Erenna® IL-2 Immunoassay Kit |
03-0051-xx |
IL-21 |
Erenna® IL-21 Immunoassay Kit |
03-0014-xx |
IL-22 |
Erenna® IL-22 Immunoassay Kit |
03-0059-xx |
IL-4 |
Erenna® IL-4 Immunoassay Kit |
03-0052-xx |
IL-5 |
Erenna® IL-5 Immunoassay Kit |
03-0053-xx |
IL-6 |
Erenna® IL-6 Immunoassay Kit |
03-0010-xx |
IL-8 |
Erenna® IL-8/CXCL8 Immunoassay Kit |
03-0055-xx |
TNFα (human) |
Erenna® Human TNFα Immunoassay Kit |
03-0022-xx |
VEGF-A (human) |
Erenna® Human VEGF Immunoassay Kit |
03-0068-xx |