Lower Limit of Detection |
0.024 pg/mL |
Lower Limit of Quantification2 |
0.2 pg/mL |
Upper Limit of Quantification |
100 pg/mL |
Low-end CV% Range |
2 - 20% |
Low-end CV% Average |
11% |
Recommended Sample Volume |
100 μL |
Minimum Sample Volume Required3 |
10 μL |
Representative data shown for demonstration purposes only. Individual results may vary depending upon samples tested and protocol used.
TInterleukin-22 (IL-22), also known as IL-10-related T-cellderived inducible factor (IL-TIF), is a member of the IL-10 cytokine family. Mainly produced by activated T-cells and natural killer cells, IL-22 binds to a receptor complex with two components, CRF2-4 and IL-22R. The signaling cascade is said to up-regulate pro-inflammatory cytokines and antimicrobial peptides, and induce production of acutephase reactants in liver and hepatoma cells. The biological function of IL-22 is associated with many inflammatory disorders, including Crohn’s disease, inflammatory bowel disease, psoriasis, rheumatoid arthritis and ulcerative colitis. Thus, IL-22 remains an attractive therapeutic target because of its pro-inflammatory properties.
Protein Name: |
Interleukin-22 |
UniProtKB/Swiss-Prot ID: |
Q9GZX6 |
Protein-protein interaction database: |
Q9GZX6 |
Alternative Names: |
Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor |
Gene Names: |
IL22 |
Synonym Gene Names: |
ILTIF, ZCYTO18 |
Function: |
Cytokine that contributes to the inflammatory response in vivo. |
Biological Processes: |
acute-phase response, cell-cell signaling |
Molecular Function: |
cytokine activity, interleukin-22 receptor binding |
|
G-CSF |
Erenna® G-CSF Immunoassay Kit |
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GM-CSF |
Erenna® GM-CSF Immunoassay Kit |
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IFN-γ |
Erenna® IFN-γ Immunoassay Kit |
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IL-1α |
Erenna® IL-1α Immunoassay Kit |
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IL-1β |
Erenna® IL-1β Immunoassay Kit |
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IL-10 |
Erenna® IL-10 Immunoassay Kit |
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IL-12 |
Erenna® IL-12 Immunoassay Kit |
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IL-13 |
Erenna® IL-13 Immunoassay Kit |
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IL-15 |
Erenna® IL-15 Immunoassay Kit |
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IL-17A |
Erenna® IL-17A Immunoassay Kit |
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IL-17A/F Heterodimer |
Erenna® IL-17A/F Heterodimer Immunoassay Kit |
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IL-17F |
Erenna® IL-17F Immunoassay Kit |
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IL-2 |
Erenna® IL-2 Immunoassay Kit |
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IL-21 |
Erenna® IL-21 Immunoassay Kit |
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IL-4 |
Erenna® IL-4 Immunoassay Kit |
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IL-5 |
Erenna® IL-5 Immunoassay Kit |
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IL-6 |
Erenna® IL-6 Immunoassay Kit |
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IL-8 |
Erenna® IL-8/CXCL8 Immunoassay Kit |
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TNFα (human) |
Erenna® Human TNFα Immunoassay Kit |
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VEGF-A (human) |
Erenna® Human VEGF Immunoassay Kit |
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