These tests show how inflammation may be impacting your health. Inflammation is the body’s natural response to injury or infection. However, chronic inflammation may lead to cholesterol-rich build-up (called plaque) in the arteries. This build-up may block arteries, trigger a heart attack or stroke, or cause other problems in the body.
SMC Endothelin* — can cause blood vessels to tighten, which can raise blood pressure. A high level may predict how far along blood vessel disease has progressed and may also be related to chronic heart failure, kidney disease, sleep apnea, or diabetes.
SMC IL-6* (interleukin- 6), SMC IL-17A* (interleukin- 17A), and SMC TNF-α* (tumor necrosis factor- alpha). These inflammatory markers are released into the bloodstream during the process of inflammation, which may cause plaque build-up in the arteries. If left untreated, this build-up can increase your risk of having a heart attack or stroke.
SMC IL-10*. This blood test is an anti-inflammatory marker. Low levels may indicate an inability to fight off inflammation.
Lp-PLA2 Activity (lipoprotein-associated phospholipase A2). High levels can be a warning sign that inflammation and rupture prone plaque may be present in arteries, increasing risk for heart attacks and strokes.
Homocysteine can be a risk marker for heart disease if the levels are elevated. High levels may also indicate that vitamin levels of B12 and B6 are too low.
hs-CRP (high-sensitivity c-reactive protein) – A high result is another warning sign of inflammation in your body, which may cause plaque build-up in your arteries, and increase your risk of a heart attack or stroke.
Anti-CCP and Rheumatoid Factor – These tests measure antibodies present in patients who may have rheumatoid arthritis (RA). A positive result for either test helps identify RA. When both tests are positive, the chance RA is present is even higher.5